- 회사소개
- 연구개발
- 사업분야
- IR / PR
- 공지사항
R & D
Pressure Ulcer / Wound Healing
Pressure Ulcer / Wound Healing Overview
- Pressure ulcers are localized injuries to the skin and/ or underlying tissue that usually occur over a bony prominence as a result of pressure. Prevalence of pressure ulcer cases are increasing dramatically due to the aging population, and there are no readily available therapeutic treatment options.
- The wound is classified into details according to the cause of the injury, but is commonly referred to as a wound in which the continuity of the normal structure of the skin tissue has been destroyed. The re-epithelialization process is essential for the healing of the wound, and the movement of the keratinocyte is considered to play an important role.
Classification of Wounds
Categorization by Severity
"Used with permission of the National Pressure Ulcer Advisory Panel."
(Source: 2016 National Pressure Ulcer Advisory Panel, Knightime Designs)
Pressure Ulcer Market
(Source: Overall Results from the 2011 International Pressure Ulcer Prevalence™ Survey)
- The prevalence of patients with pressure ulcers are mainly focused in stage 2
- Stages 2 & 3 patients can be restored to stage 1 through treatment
- Pressure ulcer incidence and prevalence is constantly increasing due to aging
Necessity of Therapeutic Reagent for Pressure Ulcers
EG-Decorin Highlights
In-vivo Proof of Concept
-
Diabetic mice pressure ulcer model
Clinical Trial Status
-
Preclinical
efficacy/
pharmacology
test complete2011
-
Preclinical
toxicology tests
complete2012
-
MFDS phase 1/2
approval (KR)2013
-
phase 1/2 step1
complete (KR)2016
-
MFDS Phase
1/2 step2
approval (KR)
2016
-
MFDS Phase2
approval (KR)
for wound healing2019
-
MFDS Phase 1/2
complete (KR)
for pressure ulcer2020.02
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